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KMID : 0391519930010020074
Journal of the Korean Child Neurology Society
1993 Volume.1 No. 2 p.74 ~ p.81
Benign epilepsy of chilhood with centrotemporal spikes: Short term prognosis and prognostic factor
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Abstract
Objective. To identify the short-term prognostic factor, and also assess the clinical and EEG changes following treatment.
Patient-and Method. We reviewed the medical record of 24 patient who followed up more than 12 month, and compared seizure control rate as a pedictor according to sex, age at onset, seizure type, ferequency. BECCT was diagnosed as following
criteria: 1)
nocturnal seizures or hemifacial seizure on wakening state, 2) normal intelligence and no abnormal neurologic sign, 3) normal EEG background activity with monomorphic sharp or spike acticity which increase the frequence during sleep if sleep EEG
was
available.
@ES Result.
@EN 1) Age at onset was range from 3 years to 11 years (7.1¡¾1.9) and patient were followed up from 12 months to 92 months.(34.8¡¾25.1)
2) Seizure was free in 54.2% of patients l month after therapy, in 75.0% 6 month after, in 83.3% l year after, in 95.8% 2 year after. We found that seizure frequence before treatment was the most important predictor (P<0.05), and also found that
male
older age at onset had more fovorable outcome of prognosis during follow up.
3) Partial seizures were increased from 54.2% before therapy to 83.2% after therapy and seizure pattern tend to become localized to the face.(P<0.05).
4) Epileptiform discharge did not disappear from the EEG during short-term follw up.
Conclusion Although BECCT recurred frequently during short-term follow, BECCT has not only an excellent long term prognosis but also mild seizure localized to the face following treatment. It would be better to avoid heavy dose of AED or
polytherapy,
and we tound the age onset, frequence of seizure as predictor of the seizure relapse.
KEYWORD
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